I was more talking about the fpe achievable in .25 vs .22. The consensus is that it will be tough to get a .22 into the 60's or low 70's. The volume of air in the barrel itself is less, so less potential for energy transfer. Also a 36+ grain .22 will be longer than a .25, so there's more friction loss getting the slug out of the barrel. Now that I type it out like that, it's probably a combination of those factors that make it difficult to get higher fpe out of a .22. At least with any meaningful number of shots.It's more Ballistic Coefficient (BC). The aerodynamics of the Slug. The higher the BC, or more aerodynamic the slug is, the longer it can travel at the same speed and be less affected by wind of comparable weighted slug.
So, a 34gr .25 slug will be less aerodynamic than a 34gr .22 slug in general. It's a game of inches. Both weigh the same, 34gr, but the slug with a higher BC will travel flatter and have less movement with wind.
The plenum isn't just about getting more fps, but, probably more importantly, consistency shot to shot. The larger air volume reservoir at reg pressure gives you less psi drop off as the projectile travels down the barrel. This helps move the projectile faster with less variance on the next shots until you fall off the reg.
Mine are .25 so unfortunately I can't be of help on you're main question.